Introducing Bacospore®.
A standardized, spore-forming Heyndrickxia coagulans MTCC 25308 probiotic, manufactured through controlled fermentation for digestive-health supplements, functional foods and nutraceutical formulations.
"The spore coat provides structural defense against acidic and challenging environmental conditions across gastrointestinal passage."
Stable spore-forming probiotic, engineered by biology.
Bacospore® is a stable, spore-forming probiotic preparation containing Heyndrickxia coagulans, formerly Bacillus coagulans. Unlike many non-spore-forming probiotics, its resistant spores are designed to tolerate acidic and challenging environmental conditions, supporting delivery through the gastrointestinal tract.
Bacospore® is standardized for viable spores and manufactured using a controlled fermentation process. The strain can produce short-chain organic acids, bacteriocin-like substances, exopolysaccharides and digestive enzymes: a profile associated with intestinal microbial balance, digestive comfort, nutrient utilization and gastrointestinal health.
- MTCC 25308
- ATCC PTA-126364
- GMO Free
- BSE / TSE Free
- Non-Irradiated
- ETO-Free
- Made in India
Four pillars for the formulator's technical review.
Mechanism
Spore survival, microbial balance, lactic acid production, gut-barrier support and beneficial metabolites.
Explore the MechanismResearch
Laboratory and preclinical research on MTCC 25308: gastroprotection, diarrhea, oxidative stress, cholesterol, adipocyte metabolism.
View the ResearchStrain Identity
A clearly identified and deposited probiotic strain: Heyndrickxia coagulans MTCC 25308 and ATCC PTA-126364.
Explore Strain IdentityGrades & Specs
Standardized at up to 300 billion viable spores per gram, with defined release specifications.
View Grades & SpecsWhat Bacospore® produces.
Bacospore®'s functional activity is not based on a single standardized phytochemical. The strain produces a set of microbiology-derived components identified in the product overview and associated with intestinal microbial balance.
Short-Chain Organic Acids
Produced during microbial metabolism and associated with intestinal environmental support.
Bacteriocin-Like Substances
Microbial substances that may help limit the growth of undesirable organisms.
Exopolysaccharides
Biologically active microbial polymers associated with probiotic functionality and microbial interactions.
Amylases & Proteases
Enzymes associated with the digestion of carbohydrates and proteins and improved nutrient utilization.
Six research-backed positioning areas.
Healthy Intestinal Microflora
Helps maintain a balanced gastrointestinal microbial environment.
Digestive Comfort
Supports normal digestion, stool consistency and gastrointestinal function.
Gut-Barrier Integrity
Helps maintain epithelial and intestinal-barrier function.
Nutrient Digestion & Absorption
Produces enzymes and metabolites associated with digestive efficiency.
Immune Function
Supports interactions between the intestinal microbiome and normal immune responses.
Antioxidant & Metabolic Support
Preclinical findings indicate antioxidant activity and effects on cholesterol and adipogenic pathways.
Multifunctional preclinical evidence.
In an ethanol-induced gastric-ulcer model, Bacospore® administration significantly reduced the ulcer index. Laboratory evaluations also reported dose-dependent antioxidant activity and cholesterol reduction. These findings support further investigation of Bacospore® for gastrointestinal, metabolic and cellular-protection applications.
- Ulcer Inhibition
- 80.4%
- Ulcer Inhibition
- Ethanol-induced gastric ulcer model
- Diarrhea Inhibition
- 26.6%
- Diarrhea Inhibition
- Castor-oil model at 200 mg/kg
- Collagenase Inhibition
- 85.4%
- Collagenase Inhibition
- Assay at 200 µg/mL
- Cholesterol Reduction
- 97.72%
- Cholesterol Reduction
- Assay at 1,000 µg/mL
- IC₅₀ (µg/mL)
- 54.19
- IC₅₀ (µg/mL)
- Comparative antioxidant activity
Technical documents for your evaluation.
Product Presentation
Overview of Bacospore®, strain identity, benefits and formulation positioning.
Download PPTResearch Dossier
Studies covering gastroprotection, antidiarrheal activity, antioxidant, cholesterol and metabolic pathways.
Download DossierProduct Specification
Viable spore count, physical properties, heavy-metal limits and microbiological requirements.
Download SpecSample COA
A representative batch-quality document for technical evaluation.
Download Sample COATechnical Data Sheet
Taxonomy, morphology, microbial characteristics, available strength and storage guidance.
Download TDSVideos & Scientific Media
Fermentation, spore stability, gastrointestinal delivery and mechanism-of-action animations.
View Videos
Manufactured by Star Hi Herbs Pvt. Ltd.
Star Hi Herbs Pvt. Ltd. develops and manufactures standardized botanical ingredients, nutraceutical products and probiotic preparations for the dietary-supplement and functional-food industries.
Bacospore® is supported by the company's research team in Bengaluru and manufactured at Star Hi Herbs Pvt. Ltd., Unit-2 SEZ, located in the Pharma SEZ at Hassan, Karnataka, India. Fermentation is identified as the manufacturing process and India as the country of origin.
- ISO 9001:2015
- GMP Certified
- Hassan SEZ · Karnataka
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Evaluate Bacospore® for your next dietary supplement, functional food or nutraceutical formulation. Please include your target viable count, dosage form, annual quantity and destination market so our technical and commercial teams can recommend the appropriate grade.