Research Highlights

An expanding strain-specific research programme.

The scientific evidence for Bacospore® MTCC 25308 is continuing to develop through research focused specifically on this strain. The current research portfolio includes two published peer-reviewed studies and one manuscript in press, investigating its potential across key areas of gastrointestinal and metabolic health.Research to date has explored gastrointestinal protection, lipid and cholesterol metabolism, collagen preservation, antioxidant activity, and adipogenic pathways, providing a broader understanding of the strain's biological and functional characteristics. As research progresses, these findings contribute to a growing, strain-specific evidence base for B. coagulans MTCC 25308.

Research at a glance.

5
Strain-specific research endpoints
2
Strain-specific pre-clinical studies
2
Peer-reviewed publications
1
Manuscript in press

Study index.

YearStudyModelKey outcome
2026Strain-Specific Modulation of Oxidative Stress, Carbohydrate Metabolism and Adipogenesis by Probiotic Bacillus spp. in 3T3-L1 Cells3T3-L1 cells, four Bacillus strainsStrongest antioxidant activity of the four strains; high cell viability.
2026 · in pressEvaluation of Antidiarrheal, Antiulcer, Anti-Collagenase and Cholesterol-Lowering Activity of Heyndrickxia coagulans MTCC 25308Ethanol-ulcer & castor-oil diarrhoea in rats; in-vitro assays80.4% ulcer inhibition · 26.6% diarrhoea inhibition · 85.40% collagenase · 97.72% cholesterol reduction.

How we label our evidence.

Because probiotic characteristics and effects can vary between strains, we clearly identify the exact strain evaluated in every study presented on this website. Research specific to Bacospore® includes laboratory, cellular, and animal studies. This distinction ensures that the evidence is presented transparently and that strain-specific findings are clearly separated from broader research on the species. The statements presented on this website have not been evaluated by the FDA or EFSA. Bacospore® is not intended to diagnose, treat, cure, or prevent any disease.

Evaluate Bacospore® in your next formulation.